LIFE SCIENCE · BIOSENSORS

Biosensor / CMOS / Cantilever

Biosensor or CMOS chip with patterned structures for precision microdispensing applications

Biosensor microdispensing enables the precise deposition of biological materials onto detection systems designed to identify and measure specific substances. They typically consist of a biological part, such as an enzyme, antibody, or DNA fragment, and a sensor that changes the biological reaction into a measurable signal. Biosensors are widely used in medical diagnostics, life science, food safety, and environmental monitoring. The labeling process can be eliminated by using CMOS – complementary metal-oxide semiconductor, where the detection is changed into an electrical signal.


These modern CMOS-based biosensors offer additional advantages, including compact size, low cost, real-time detection, and high sensitivity, making them ideal for portable and point-of-care testing devices.
The efficiency of the biosensors depends on the accurate and precise placement of the biological material on the sensor. Precise, reliable and well controlled ultra-low volume liquid positioning.
For many years, microdrop has provided high-throughput dispensing solutions that enable deposition of the liquids in picoliter, nanoliter and microliter volumes. With a new additional feature, such as QC on the Fly the manufacturing capacity can grow even faster, with the factor 5-10x compared to the traditional technology suppliers.


microdrop Technologies offers tailor-made solutions to the specific chip-layout and additional features like humidity and temperature control, or customised software solutions. The fastest inkjet printing technology, with extremely high accuracy, can handle nearly any viscosity or liquid variation.

Microdispensing for Biosensor Applications

Biosensor Application Highlights:

  • Highly precise dispensing for biosensor manufacturing and functionalization
  • Reproducible deposition of biological and functional materials
  • Scalable automation platforms for industrial biosensor production

Typical Biosensor, CMOS & Cantilever Applications:

Biosensor Applications CMOS-Based Sensor Application Cantilever Application
  • Biomarker detection
  • Infectious disease diagnostics
  • Point-of-care tesing
  • Food & environmental sensing
  • Electrical signal detection
  • Portable diagnostics devices
  • High-sensivity sensing
  • Integrated lab-on-a-chip systems
  • Surface functionalization
  • Molecular interaction analysis
  • Force and mass sensing
  • Research and micro-/ nano-scale detection

... and much more.

APPLICATION NOTE

Cantilever Biosensor – Biological Activation

microdrop dispenser depositing droplets onto a cantilever biosensor

microdrop Dispensing Technology is a powerful tool for surface activation and functionalisation with different biomolecules at Cantilever based biosensors. These sensors operate label-free, and do not require chemical tags or conjugates for delivering real-time results.

Workflow showing microdrop dispensing onto a cantilever biosensor and laser-based readout

Source: The images and videos used here originate from research of Prof. Martin Hegner’s group at Trinity College Dublin.

APPLICATION NOTE

Polymer Gas Biosensor or Glass Based Biosensor Microdispensing

Polymer microdroplet sensor used for optical gas sensing

In the research group of Dr. Marc-Antoine Bianki at Polytechnique Montréal, they successfully utilized microdrop Dispensing Technology to design and test various optical gas sensor prototypes. The measuring of the concentration of different gases within mixtures using integrated polymer microdroplets sensor.

Source: Research by Dr. Marc-Antoine Bianki at Polytechnique Montréal.

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Product Information

Autodrop Pipettes
Picoliter dispensing technology
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Gantry ECO
Compact benchtop microdispensing system
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Gantry II S
Flexible multichannel microdispensing system
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Gantry II P
Customizable production microdispensing system
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